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Details

Project TitleIntegrated Biosensor using Microspheres
Track Code4799
Short Description

Cornell researchers have developed an on-chip label-free biosensor fabricated with standard lithography techniques.

Abstract

The invention relies on unique integrated waveguides that optically trap microspheres in a microfluidic channel. Light transmitted through the waveguide circulates thousands of times around the trapped spheres and these resonances are measured to monitor binding of biomolecules (the microspheres are functionalized such that analytes of interest will bind to them). By observing characteristics such as absorption and refractive index, individual biomolecules can be readily identified. The invention holds great promise in particular for diagnostics where label-free sensing is crucial.

 


                       

Potential Applications

  • Various biosensor applications including diagnostics

                             

Advantages

  • Label-free biosensing
  • On-chip format
  • Uses standard fabrication techniques
 
TagsBiological Nanofabrication, cmos, fiber optics, life science, Optics & Photonics, physical science, Sensor External Use, sensors
 
Posted DateJul 24, 2012 8:55 PM

Researcher

Name
Michal Lipson
Arthur Nitkowski

Additional Information

Licensing Contact

Patrick Govang

pjg26@cornell.edu

(607) 254-2330