Skip to main content
 
HOME FOR INVENTORS FOR INDUSTRY FOR ENTREPRENEURS
 

Details

Project TitleFabrication of Vascular Engineered Tissue Using Sacrificial Structures
Track Code4343
Short Description

Cornell researchers have developed a novel technique for fabricating three-dimensional vascular networks made up of thousands of microchannels in a polymer matrix.

Abstract

Cornell researchers have developed a novel technique for fabricating three-dimensional vascular networks made up of thousands of microchannels in a polymer matrix. The technique is compatible with a wide range of materials, and is based on the use of a sacrificial, melt-spun material. This fibrous material is arranged on a substrate and a selected polymer is poured over it. After the polymer has cured, the sacrificial material can be washed away.

  

The resulting microchannel-filled materials have a wide range of useful applications. They provide excellent, highly vascular, tissue engineering constructs perfect for reconstructive surgery and wound healing applications. The fluidic structures also serve as ideal carriers of healing agents used in self-healing polymer materials, allowing these technologies to be expanded beyond coatings into larger scale materials. The high surface area vascular networks of course also serve as an ideal environment for various microfluidic processes (heat exchange, etc.).

  

Potential Applications

  • Tissue engineering, including reconstructive surgery and would healing
  • Self-healing polymer materials
  • Microfluidics

   

Advantages

  • Low cost
  • Highly scalable
  • Non-toxic
  • Microchannels extend in all three dimensions
 
TagsAesthetics - Cosmetic, life science, tissue engineering, wound healing, physical science
 
Posted DateJul 23, 2012 12:43 PM

Researcher

Name
Harold Craighead
Leon Bellan
Jason Spector

Additional Information

Licensing Contact

Martin Teschl
mt439@cornell.edu
(607) 254-4454